Searchable abstracts of presentations at key conferences in endocrinology

ea0007p273 | Clinical case reports | BES2004

Development of GH secretion and malignant change in a giant prolactinoma

Howell S , Parkington S , Roberts G , Vice P

A 49 year old man presented in 1998 with marked visual disturbance. MRI scan revealed a very large pituitary tumour with compression of the anterior optic pathways. Prolactin was markedly elevated at 259,000 milliunits per litre confirming the diagnosis of a giant prolactinoma. A trial of dopamine agonist therapy did not result in any improvement in vision and he proceeded to pituitary surgery. Vision improved and prolactin levels were suppressed by dopamine agonist therapy wi...